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Scientific Advisory Board


TDI’s first 6 years have focused on the development of its key protein isoform resolving technologies (IDBEST™ and Isonostic™ CZE platforms). During this time it has been served well by a Scientific Advisory Board of proteomic technology specialists. With completion of the development of these core platform technologies, the composition of TDI’s Scientific Advisory Board will evolve to include leading pathology and oncology researchers in the specific areas of clinical focus being addressed.

Dr. John E. Shively is Chairman of the Division of Immunology at the Beckman Research Institute of the City of Hope, as well as Associate Dean, City of Hope Graduate School, and Professor of Immunology at City of Hope. Dr. Shively holds degrees in Chemistry (B.S.), Biochemistry (M.S.) and received his Ph.D. in Biochemistry from University of Illinois. In addition to authoring over 300 publications, Dr. Shively currently serves on the Editorial Board of Tumor Biology. Following earlier leadership roles with the Protein Society, NCI Ad Hoc Committees, and American Heart Research Committee and Review Panel, Dr. Shively continues to serve on NCI F Committee. Dr. Shively was the recipient of the ISOBM Abbott Award in 1999.

Dr. Juan G. Santiago, Director of the Stanford Microfluidics Laboratory, has Ph.D. in Mechanical Engineering from the University of Illinois at Urbana-Champaign (UIUC). At UIUC, he received four fellowships as a doctoral candidate (including fellowships from NSF and Exxon Corp.), and a UIUC Teaching Fellow Award. He was a Senior Member of the Technical Staff at the Aerospace Corporation ('95 - '97), where his work included the development of flow diagnostics for micronozzles. Prof. Santiago received a Ford Foundation Postodoctoral Fellowship ('97), and worked as a Research Scientist at UIUC’s Beckman Institute ('97 - '98). Santiago is an Associate Professor in the Mechanical Engineering Department at Stanford. He specializes in micro-scale fluid mechanics, micro-scale optical flow diagnostics, and microfluidic system design. His research includes the investigation of transport phenomena and optimization of microsystems for pumping liquids, electrophoretic injections and separations, sample concentration methods, and rapid micromixing processes. The applications of this work include microfabricated bioanalytical systems for genetic analysis and drug discovery. He has received a Frederick Emmons Terman Fellowship ('98-'01), won the National Inventor’s Hall of Fame Collegiate Inventors Competition ('01), and was awarded a National Science Foundation PECASE Award ('03-'08).

Dr. Alan J. Smith, retired, was the Director of the Protein and Nucleic Acid (PAN) Biotechnology Facility and a Member of Department of Molecular and Genetic Medicine, at Stanford University Medical School. PAN provides a service function associated with proteins, synthetic peptides, synthetic and biosynthetic DNA, and gene expression analysis, as well as a technology development function to support existing and new applications of these and other technologies. Dr. Smith has published over 50 peer-reviewed publications, including several book chapters. He has been involved in the development of several novel chemical processes and instrumentation platforms, and serves on several NIH/NCI instrumentation study sections and government-funded site inspection teams. Dr. Smith co-founded the International Association of Biotechnology Support Laboratories (ABRF) and served on the Executive Board and chaired several research committees within that organization. He serves on the Executive Board of the California Separation Science Society (CaSSS) and is a member of the Howard Hughes Medical Institute. Dr. Smith is the co-founder of a biotechnology startup company making synthetic DNA.

Dr. Evan R. Williams, Professor of Chemistry and Biophysics at the University of California at Berkeley and a Chemist Faculty in the Physical Biosciences Division at the Lawrence Berkeley National Laboratory, serves as the Associate Director of the Center for Analytical Biotechnology at UC Berkeley. Professor Williams' research encompasses development of novel instrumentation and computational techniques in mass spectrometry, tandem mass spectrometry, separations, and spectroscopy for probing the structure and function of biomolecules, applications of new dissociation methods for rapid protein identification, and development of novel sample introduction methods for mass spectrometry. Professor Williams has published over 75 papers, given over 100 invited talks and has several patents in the area of mass spectrometry. He has received numerous awards, including the Alexander von Humboldt Senior Scientist Award (1999), the American Society for Mass Spectrometry Research Award (1994) the Exxon Education Foundation Research Award (1993), the National Science Foundation Young Investigator Award (1992) and the Arnold and Mabel Beckman Young Investigator Award (1992). He currently serves on the Editorial Boards of the Journal of the American Society for Mass Spectrometry (2001-) and the International Journal of Mass Spectrometry (1997-), and on the ACS Canvassing Committee for the Field and Franklin Award for Outstanding Achievements in Mass Spectrometry (2000-), and the Advisory Panel of the NSF National High Magnetic Field FT/ICR Facility (1998-). He also serves as an Associate Director of the California Separation Science Society (1992-). Professor Williams was a NSF postdoctoral fellow at Stanford University and received a Ph.D. and M.S. in chemistry from Cornell University and a B.S. in chemistry from the University of Virginia.

Dr. Leon S. Yengoyan, is Professor of Chemistry and serves on the Tenure, Retention and Promotion Committee at San Jose State University. Following a B.S. in Chemistry, Dr. Yengoyan received a Ph.D. in Chemistry/Biochemistry from Stanford. He completed post-doctoral work at the National Research Council of Canada, as an NIH Fellow working with Nobelist Dr. Cornforth in England, and at the Syntex Institute of Molecular Biology. Dr. Yengoyan is a recognized expert in biochemistry methodology and separation science, serving as an expert witness, on 2 Scientific Advisory Boards, and authoring several papers, presentations and patent applications. He maintains an active teaching curriculum, as well as over 20 industrial consulting relationships, and conducts NSF, NIH and privately funded.

  





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